Loading…
skip to main content
Hypersensitivity
Hypersensitivity81128
Please enable Javascript

MEDICAL ANIMATION TRANSCRIPT: Our body protects us from many environmental substances such as pollen, foreign chemicals, and pathogens. The immune system is a surveillance system of specialized white blood cells and tissues that recognize self from foreign matter. An antigen is any foreign environmental substance that elicits an immune response. Antibodies are proteins developed by the immune system that recognize and bind antigens. Sometimes our immune system responds excessively to antigens, causing inflammation and tissue damage. This is called an allergic response. Antigens causing an allergic response are allergens. There are four major types of hypersensitivity, immediate, cytotoxic, immune complex, and delayed. The most common type of hypersensitivity is type one, or immediate. This type includes allergies elicited by antigens such as pollen. After initial exposure to this allergen, immune cells create immunoglobulin E antibodies for subsequent exposures. These antibodies are bound to certain white blood cells called mast cells and basophils. Immunoglobulin E encounters and binds to the allergen, triggering the release of inflammatory substances such as histamines, prostaglandins, and leukotrienes from mast cells and basophils. If severe and left untreated, type one can lead to anaphylaxis, an acute, life threatening condition that occurs quickly after antigen exposure and is characterized by low blood pressure and difficulty breathing. Treatment of type one hypersensitivity or allergic reactions induced by environmental substances or biological agents includes treatment of mild symptoms with over-the-counter antihistamines, corticosteroids, or immunosuppressive medications, treatment of severe reactions and anaphylaxis with an epipen, discontinued exposure to the environmental agent, and if the hypersensitivity is in response to a necessary drug treatment, substitution with another agent. In some cases, no reasonable alternative exists, in which case a regimen of desensitization by repeated and monitored exposure to low doses of the drug or agent may be necessary. ♪ [music] ♪

ANM11036 03:53

Last Updated: Apr 24th, 2020

Keywords
No keywords have been added.

Nucleus Medical Media Disclaimer of Medical and Legal Liability

Nucleus Medical Media ("Nucleus") does not dispense medical or legal advice, and the text, illustrations, photographs, animations and other information ("Content") available on this web site is for general information purposes only. As with any medical or legal issue, it is up to you to consult a physician or attorney for professional advice. YOU SHOULD NOT DISREGARD PROFESSIONAL MEDICAL OR LEGAL ADVICE BASED ON CONTENT CONTAINED ON THIS WEB SITE, NOR SHOULD YOU RELY ON THE CONTENT ON THIS WEB SITE IN PLACE OF PROFESSIONAL MEDICAL OR LEGAL ADVICE.

NUCLEUS DISCLAIMS ALL RESPONSIBILITY AND LIABILITY FOR ANY COUNSEL, ADVICE, TREATMENT, DIAGNOSIS OR ANY MEDICAL, LEGAL OR OTHER INFORMATION, SERVICES OR PRODUCTS THAT YOU OBTAIN BASED ON VIEWING THE CONTENT OF THIS SITE. THE INFORMATION ON THIS WEB SITE SHOULD NOT BE CONSIDERED COMPLETE OR SUITABLE FOR ANY PURPOSE WHATSOEVER.

Mature Content Disclaimer: Certain Content on this web site contains graphic depictions or descriptions of medical information, which may be offensive to some viewers. Nucleus, its licensors, and its suppliers disclaim all responsibility for such materials.

close